PRELP Rabbit pAb - A18573

PRELP Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A18573-20, A18573-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Mouse, Rat

Protein Weight: 44kDa

Observed Molecular Weight: 44kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 5549

SWISS: P51888

Alternate Names: MST161; SLRR2A; MSTP161; PRELP

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Extracellular Matrix, Bone.

NCBI Alias: PRELP

Research Use Only