PRK2 Monoclonal Antibody - BT-MCA1062

PRK2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1062-50, BT-MCA1062-100

Citations, Manuals and MSDS Available upon request.

Background: Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids. Two specific sites, Thr-816 (activation loop of the kinase domain) and Thr-958 (turn motif), need to be phosphorylated for its full activation.,function:Exhibits a preference for highly basic protein substrates.,PTM:Activated by limited proteolysis with trypsin.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 C2 domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 REM (Hr1) repeats.,

Research Areas: Signal transduction

Target Protein: PKN2

Applications: WB, IHC-p, IF, FCM, ELISA

Reactivity: Human,Mouse,Rat,Monkey

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Serine,threonine-protein kinase N2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q16513; Mouse: Q8BWW9; Rat: O08874

Synonyms: PKN2; PRK2; PRKCL2; Serine; threonine-protein kinase N2; PKN gamma; Protein kinase C-like 2; Protein-kinase C-related kinase 2

GeneID: Human: 5586; Mouse: 109333

Research Use Only