PRKACA Monoclonal Antibody - BT-MCA3077

PRKACA Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3077-50, BT-MCA3077-100

Citations, Manuals and MSDS Available upon request.

Background: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Research Areas: Others

Target Protein: PRKACA

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2E3B7

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: PRKACA

Immunogen: Purified recombinant fragment of human PRKACA (AA: 1-120) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Molecular Weight (Da): 40.6kDa

UniProt Accession: P17612

Synonyms: PKACA

GeneID: 5566

Research Use Only