PRKDC Monoclonal Antibody - BT-MCA3152

PRKDC Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3152-50, BT-MCA3152-100

Citations, Manuals and MSDS Available upon request.

Background: The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: PRKDC

Applications: IHC, ICC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3H6

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: PRKDC

Immunogen: Purified recombinant fragment of human PRKDC expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 46.9kDa

UniProt Accession: P78527

Synonyms: HYRC, p350, DNAPK, DNPK1, HYRC1, XRCC7, DNA-PKcs, PRKDC

GeneID: 5591

Research Use Only