PRMT1 Monoclonal Antibody - BT-MCA1063

PRMT1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1063-50, BT-MCA1063-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

Research Areas: Epigenetics and nuclear signaling; Cell biology; Cancer

Target Protein: PRMT1

Applications: WB

Reactivity: Human,Mouse,Rat,Dog,Rabbit

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Protein arginine N-methyltransferase 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q99873; Mouse: Q9JIF0; Rat: Q63009

Synonyms: PRMT1; HMT2; HRMT1L2; IR1B4; Protein arginine N-methyltransferase 1; Histone-arginine N-methyltransferase PRMT1; Interferon receptor 1-bound protein 4

GeneID: Human: 3276; Mouse: 15469; Rat: 60421

Research Use Only