Protein Z Monoclonal Antibody - BT-MCA1069

Protein Z Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1069-50, BT-MCA1069-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.

Research Areas: Neuroscience

Target Protein: PROZ

Applications: WB, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Vitamin K-dependent protein Z

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P22891; Mouse: Q9CQW3

Synonyms: PROZ; Vitamin K-dependent protein Z

GeneID: Human: 8858

Research Use Only