Proteinase 3 Monoclonal Antibody - BT-MCA3445

Proteinase 3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3445-50, BT-MCA3445-100

Citations, Manuals and MSDS Available upon request.

Background: Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.

Research Areas: Others

Target Protein: Proteinase 3

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3B4

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: Proteinase 3

Immunogen: Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 28kDa

UniProt Accession: P24158

Synonyms: PRTN3, ACPA, CANCA

GeneID: 5657

Research Use Only