PSAP Monoclonal Antibody - BT-MCA2786

PSAP Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2786-50, BT-MCA2786-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Research Areas: Signal Transduction, Metabolism

Target Protein: PSAP

Applications: WB, IHC, ICC, FCM

Clonality: Monoclonal

Clone ID: 3B4A8

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: PSAP

Immunogen: Purified recombinant fragment of human PSAP (AA: 17-216) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 58.1kDa

UniProt Accession: P07602

Synonyms: GLBA, SAP1, SAP2

GeneID: 5660

Research Use Only