PSG1 Polyclonal Antibody-BS8187

PSG1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8187-50, BS8187-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P11464

Host: Rabbit

Reactivity: Human

Applications: WB, IHC, IF

All Applications: WB: 1:500 - 1:2000
IHC:1:50 - 1:100
IF:1:50 - 1:200

Background: Pregnancy specific glycoprotein 1 (PSG1), also designated CD66f, is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein
in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. PSGs are commonly expressed in trophoblast tumors. 11 human PSG proteins (PSG1-PSG11) have been described.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 180-419 of human PSG1

Bioworld Molecular Weight: ~ 55-72 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using PSG1 antibody at 1:1000 dilution.
Lysates/proteins: 40ug per Lane.
Exposure time: 90s., Immunohistochemistry of paraffin-embedded human colon carcinoma using PSG1 antibody at dilution of 1:100 (40x lens)., Immunohistochemistry of paraffin-embedded human stomach using PSG1 antibody at dilution of 1:100 (40x lens)., Immunofluorescence - PSG1 Rabbit pAb

Alternative Name: Pregnancy-specific beta-1-glycoprotein 1; PS-beta-G-1; PSBG-1; Pregnancy-specific glycoprotein 1; CD66 antigen-like family member F; Fetal liver non-specific cross-reactive antigen 1/2; FL-NCA-1/2; PSG95; Pregnancy-specific beta-1 glycoprotein C/D; PS-beta-C/D; CD66f; PSG1; B1G1; PSBG1; PSGGA

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-419 of human PSG1

Conjugate: Unconjugated

Modification: Unmodified