Product Description

PSMD11 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65356-50, BS65356-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: O00231

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-P, IF (paraffin section), ELISA

All Applications: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Background: proteasome 26S subunit, non-ATPase 11(PSMD11) Homo sapiens The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq,

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PSMD11 Polyclonal Antibody detects endogenous levels of PSMD11 protein.

Bioworld Molecular Weight: ~42 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of various cells using PSMD11 Polyclonal Antibody, Western blot analysis of lysates from 293 and HepG2 cells, using PSMD11 Antibody. The Lane on the right is blocked with the synthesized peptide., Western blot analysis of the lysates from RAW264.7cells using PSMD11 antibody.

Alternative Name: PSMD11; 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5

Immunogen: The antiserum was produced against synthesized peptide derived from human PSMD11. AA range:271-320

Conjugate: Unconjugated

Modification: Unmodified