PTH/PTHrP-R Monoclonal Antibody - BT-MCA1076

PTH/PTHrP-R Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA1076-50, BT-MCA1076-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

Research Areas: Signal transduction; Neuroscience

Target Protein: PTH1R

Applications: WB, IHC-p, IF, ICC, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Parathyroid hormone,kparathyroid hormone-related peptide receptor

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q03431; Mouse: P41593

Synonyms: PTH1R; PTHR; PTHR1; Parathyroid hormone; parathyroid hormone-related peptide receptor; PTH; PTHrP type I receptor; PTH; PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor

GeneID: Human: 5745

Research Use Only