Product Description

PTN2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34286-50, RA34286-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: protein tyrosine phosphatase, non-receptor type 2 (PTPN2) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 45

Protein Molecular Weight (kDa): 45

Storage: -20°C/1 year

Human Gene ID: 5771

Human SwissProt Number: P17706

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only