PTPRN2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14774-20, A14774-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4, 5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 111kDa
Observed Molecular Weight: 111kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 5799
SWISS: Q92932
Alternate Names: IAR; ICAAR; PTPRP; IA-2beta; R-PTP-N2; PTPRN2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Immunology Inflammation.
NCBI Alias: PTPRN2
Research Use Only