PTPRU Monoclonal Antibody - BT-MCA4266

PTPRU Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4266-50, BT-MCA4266-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.

Research Areas: Signal transduction

Target Protein: PTPRU

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1A6E5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: PTPRU

Immunogen: Purified recombinant fragment of human PTPRU (AA: extra 579-749) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 162.4kDa

UniProt Accession: Q92729

Synonyms: FMI, PTP, PCP-2, PTP-J, PTPRO, PTPU2, PTP-PI, PTP-RO, PTPPSI, hPTP-J, R-PTP-U, R-PTP-PSI

GeneID: 10076

Research Use Only