Product Description

Rab 18 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES5274-50, ES5274-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA, IHC

Alternate Names: RAB18, Ras-related protein Rab-18

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human RAB18. AA range:103-152

Isotype: IgG

Target: Rab 18

Specificity: Rab 18 Polyclonal Antibody detects endogenous levels of Rab 18 protein.

Dilution: WB 1:500-2000, IHC-p 1:50-300, ELISA 2000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Ubiquitous,

Observed Band (KD): 28kD

Function: Function: Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes
Similarity: Belongs to the small GTPase superfamily. Rab family
Tissue Specificity: Ubiquitous

Subcellular Location: Apical cell membrane Lipid droplet

Storage and Stability: -20°C/1 year

Gene Name: RAB18

Protein Name: Ras-related protein Rab-18

Mouse Gene ID: 19330

Mouse SwissProt Number: P35293

Rat Gene ID: 307039

Rat SwissProt Number: Q5EB77

Research Use Only