Product Description

RAB11FIP2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65265-50, BS65265-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: Q7L804

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, ELISA

All Applications: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Background: function:A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA).,similarity:Contains 1 C2 domain.,subcellular location:Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.,subunit:Homooligomerizes in a Rab11-independent manner. Forms an heterooligomeric complex with RAB11FIP4. Interacts with AP2A1, MYO5B, RAB11A, RAB11B, RAB25 and REPS1. Interacts with RAB11A/RAB11B that has been activated by GTP binding.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Rab11-FIP2 Polyclonal Antibody detects endogenous levels of Rab11-FIP2 protein.

Bioworld Molecular Weight: ~ 58 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of MCF-7 cells using Rab11-FIP2 Polyclonal Antibody, Western blot analysis of lysates from MCF-7, HUVEC, A549, and COLO cells, using RAB11FIP2 Antibody. The Lane on the right is blocked with the synthesized peptide., Western blot analysis of the lysates from HepG2 cells using RAB11FIP2 antibody.

Alternative Name: RAB11FIP2; KIAA0941; Rab11 family-interacting protein 2; Rab11-FIP2; NRip11

Immunogen: The antiserum was produced against synthesized peptide derived from human RAB11FIP2. AA range:340-389

Conjugate: Unconjugated

Modification: Unmodified