Rac1/cdc42 (Phospho-Ser71) Rabbit Polyclonal Antibody - BT-AP12225

Rac1/cdc42 (Phospho-Ser71) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12225-20, BT-AP12225-50, BT-AP12225-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a small GTPase of the Rho-subfamily| which regulates signaling pathways that control diverse cellular functions including cell morphology| migration| endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42| and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP)| which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3| 4| 5| 7| 8 and 20.

Research Areas: Signal transduction; Immunology; Cancer

Applications: WB

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Rac1/cdc42

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P60953; Mouse: P60766; Rat: Q8CFN2

Synonyms: Rac1/cdc42;Ser71; Cell division control protein 42 homolog; G25K GTP-binding protein

GeneID: Human: 998; Mouse: 12540; Rat: 64465

Research Use Only