RAC2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-40245-60, E-AB-40245-120, E-AB-40245-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: RAC2
Target Synonym: EN 7; GX; HSPC 022; HSPC022; p21 Rac 2; RAC 2; Ras related C3 botulinum toxin substrate 2; Ras related C3 botulinum toxin substrate 3 (rho family; small GTP binding protein Rac2); Ras related C3 botulinum toxin substrate 3; Rho family small GTP binding protein Rac 2; Small G protein
Research Areas: Cancer, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P15153
Background: RAC2, also named as GX, belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.
Concentration: 2 mg/mL
Immunogen: Recombinant Human Ras-related C3 botulinum toxin substrate 2 protien
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only