RAD23B Monoclonal Antibody - BT-MCA2890

RAD23B Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2890-50, BT-MCA2890-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: RAD23B

Applications: WB, IHC, ICC, FCM

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 6D2B3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: RAD23B

Immunogen: Purified recombinant fragment of human RAD23B expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 43.2kDa

UniProt Accession: P54727

Synonyms: P58, HR23B, HHR23B

GeneID: 5887

Research Use Only