Product Description

RASL2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34371-50, RA34371-100

Citations, Manuals and MSDS Available upon request.

Background: RAS p21 protein activator 4 (RASA4) Homo sapiens This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca (2+) . Stimuli that increase intracellular Ca (2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 10156

Protein MW (KDa): 88

SWISS: O43374

Source: Rabbit

Research Use Only