Product Description

RBFOX2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18996-60, E-AB-18996-120, E-AB-18996-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: RBFOX2

Target Synonym: HRNBP2; Fox 1 homologue; Fox-1 homolog B; FOX2; FXH; Hexaribonucleotide-binding protein 2; HNRBP2; RBFOX2; Repressor of tamoxifen transcriptional activity; RFOX2; RNA binding motif protein 9; RNA binding protein 9; RNA binding protein fox-1 homolog 2; RNA-binding motif protein 9; RNA-binding protein 9; RTA

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O43251

Background: This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: 1.44 mg/mL

Immunogen: Fusion protein of human RBFOX2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only