Recombinant Human Bridging Integrator 2/BIN2 Protein (His Tag) - PKSH032131

Recombinant Human Bridging Integrator 2/BIN2 Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH032131-10, PKSH032131-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: Bridging Integrator 2; BIN2

Target Synonym: Bridging Integrator 2; Breast Cancer-Associated Protein 1; BIN2; BRAP1

UNIProt ID: Q9UBW5

Research Areas: Cell biology

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-6His

Accession: Q9UBW5

Background: Bridging Integrator 2 (BIN2) is a cytoplasmic protein. BIN2 contains one BAR domain and Interacts with BIN1. BIN2 is highly expressed in some hematopoietic tissues, including peripheral blood, thymus, colon and placenta. BIN2 is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling. Genetic studies show that BIN2 is inhibited in response to BR perception at the cell surface to relieve its inhibitory effects on downstream targets.

Sequence: Met 1-Asn244

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 30.6 kDa

Observed MW: 32 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only