Recombinant Human HPGDS/GSTS Protein
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032528-10, PKSH032528-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: HPGDS; GSTS
Target Synonym: Hematopoietic Prostaglandin D Synthase; H-PGDS; GST Class-Sigma; Glutathione S-Transferase; Glutathione-Dependent PGD Synthase; Glutathione-Requiring Prostaglandin D Synthase; Prostaglandin-H2 D-Isomerase; HPGDS; GSTS; PGDS; PTGDS2
UNIProt ID: O60760
Research Areas: Signal Transduction;
Target Species: Human
Expression Host: E.coli
Fusion Tag: None
Accession: O60760
Background: Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide.
Sequence: Met 1-Leu199
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 200mM NaCl, pH 7.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 23.6 kDa
Observed MW: 26 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only