Recombinant Human SDF2 Protein (His Tag)
Size: 100μg
Catalogue Number: PKSH031339-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: SDF2
Target Synonym: SDF2
Research Areas: Signal Transduction, Cancer, metabolism,
Target Species: Human
Expression Host: Baculovirus-Insect Cells
Fusion Tag: C-His
Accession: NP_008854.2
Background: Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 and SDF-5 are not well defined and their biological functions are less known. SDF-2 is first isolated from themousestromal cell lineST2 as asecretory protein. The amino acid sequence deduced from themurineclone and thehumanhomologare conserved more than 92 %, and the aa sequence of SDF-2 shows similarity to those ofyeastdolichyl phosphate-D-mannose, protein mannosyltransferases. SDF-1 and its receptor are strongly indicated in the progression of various cancers including breast cancer. SDF-2, SDF2-L1, SDF-4, and SDF-5 are ubiquitously expressed in various cancer cell lines and SDF-2, SDF-4 and SDF-5 are expressed in mammary tissues. These SDFs have prognostic value and warrant further investigation in their biological functions and clinical value.
Sequence: Met 1-Leu 211
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 0.5mM PMSF, 0.5mM EDTA, 0.5mM TCEP, 10% glycerol
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 22.7 kDa
Observed MW: 22.7 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only