RET Monoclonal Antibody - BT-MCA4680

RET Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4680-50, BT-MCA4680-100

Citations, Manuals and MSDS Available upon request.

Background: RET (ret proto-oncogene) is a member of the cadherin superfamily and a receptor tyrosine kinase, which are cell-surface molecules that transduce signals for cell growth and differentiation. It can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Ligands that bind the Ret receptor include the glial cell line-derived neurotropic factor (GDNF) and its congeners neurturin, persephin and artemin. Alterations in the corresponding Ret gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma and a congenital developmental disorder known as Hirschsprung

Research Areas: Signal Transduction

Target Protein: RET

Reactivity: Human

Clonality: Monoclonal

Clone ID: 8D10C9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: RET

Immunogen: Purified recombinant fragment of RET (aa896-1063) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: P07949

Synonyms: RET

GeneID: 5979

Research Use Only