Product Description

RFOX1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34434-50, RA34434-100

Citations, Manuals and MSDS Available upon request.

Background: RNA binding protein, fox-1 homolog 1 (RBFOX1) Homo sapiens The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U) GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2) . Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 54715

Protein MW (KDa): 43

SWISS: Q9NWB1

Source: Rabbit

Research Use Only