Product Description

RGRF1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34457-50, RA34457-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Ras protein specific guanine nucleotide releasing factor 1 (RASGRF1) Homo sapiens The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 140

Protein Molecular Weight (kDa): 140

Storage: -20°C/1 year

Human Gene ID: 5923

Human SwissProt Number: Q13972

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only