RIN2 Polyclonal Antibody - RA34487

RIN2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34487-50, RA34487-100

Citations, Manuals and MSDS Available upon request.

Background: Ras and Rab interactor 2 (RIN2) Homo sapiens The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 54453

Protein MW (KDa): 98

SWISS: Q8WYP3

Source: Rabbit

Research Use Only