RIN2 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A13798-20, A13798-100
Citations, Manuals and SDS Available upon request.
Background: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.
Synonyms: MACS; RASSF4; RIN2
GeneID: 54453
Swiss Prot: Q8WYP3
Tested Applications: ELISA, WB
Reactivity: Human, Mouse
Calculated Molecular Weight: 100kDa
Observed Molecular Weight: 120kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Signal Transduction, G protein signaling, Small G proteins
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: 293T, A-549, HeLa, HepG2, Mouse heart, Mouse kidney
Cellular Location: Cytoplasm
Keywords: 54453, RIN2, MACS, RASSF4, Ras and Rab interactor 2, ras and Rab interactor 2, RAB5 interacting protein 2, RAS association (RalGDS/AF-6) domain containing protein JC265, RAS association domain family 4, RAS inhibitor JC265, RAS interaction/interference protein 2, Q8WYP3, Ras And Rab Interactor 2, RAS Association (RalGDS/AF-6) Domain Containing Protein JC265, RAS Interaction/Interference Protein 2, Ras Interaction/Interference Protein 2, RAS Association Domain Family 4, Ras Association Domain Family 4, RAB5 Interacting Protein 2, RAS Inhibitor JC265, Ras Inhibitor JC265
Symbol: RIN2
Category: Polyclonal Antibodies
Research Use Only