RNase Z2 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA29499-50, RA29499-100 Citations, Manuals and MSDS Available upon request. Background: elaC ribonuclease Z 2 (ELAC2) Homo sapiens The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. Alternative Names: ELAC2; HPC2; Zinc phosphodiesterase ELAC protein 2; ElaC homolog protein 2; Heredity prostate cancer protein 2; Ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z 2 Applications: IHC-p; IF (paraffin section) ; ELISA Species Cross-Reactivity: Human; Rat; Mouse GeneID (Human): 60528 SWISS: Q9BQ52 Source: Rabbit Research Use Only