RPTOR Polyclonal Antibody - BT-AP13921

RPTOR Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13921-20, BT-AP13921-50, BT-AP13921-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cell biology; Epigenetics and nuclear signaling; Signal transduction

Target Protein: RPTOR

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Regulatory-associated protein of mTOR

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8N122; Mouse: Q8K4Q0

Synonyms: Regulatory-associated protein of mTOR;Raptor;p150 target of rapamycin;TOR-scaffold protein

GeneID: Human: 57521

Research Use Only