Product Description

RSK2 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB67015-50, MB67015-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regμlates translation through RPS6 and EIF4B phosphorylation, and mediates cellμlar proliferation, survival, and differentiation by modμlating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: ISPK1, MAPKAPK1B, RSK2, Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, 90 kDa ribosomal protein S6 kinase 3, p90-RSK 3, p90RSK3, Insμlin-stimμlated protein kinase 1, ISPK-1, MAP kinase-activated protein kinase 1b, MAPK-activated protein kinase 1b, MAPKAP kinase 1b, MAPKAPK-1b, Ribosomal S6 kinase 2, RSK-2, pp90RSK2

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human RSK2. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of RSK2 protein.

Molecular Weight: ~ 83 kDa

Pathway: Regμlation of Apoptosis, Cell Cycle G2 M DNA Damage Signaling Pathway, G Protein-coupled Receptors Signaling to MAPK Erk, MAPK Erk in Growth and Differentiation Pathway, Inhibition of Apoptosis, Regμlation of Microtubμle Dynamics, Mitochondrial Control of Apoptosis, Translational Contral elF4 and p70 S6 Kinase, MTOR signaling.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P51812

Product: Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only