RTN3 Monoclonal Antibody - BT-MCA4013

RTN3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4013-50, BT-MCA4013-100

Citations, Manuals and MSDS Available upon request.

Background: RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.

Research Areas: Cell Biology, Signal Transduction, Metabolism, Cancer

Target Protein: RTN3

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 10A8

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: RTN3

Immunogen: Purified recombinant fragment of RTN3 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 113kDa

UniProt Accession: O95197

Synonyms: HAP, ASYIP, NSPL2, NSPLII, RTN3-A1

GeneID: 10313

Research Use Only