RUNX3 Monoclonal Antibody - BT-MCA3161

RUNX3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3161-50, BT-MCA3161-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: RUNX3

Applications: IHC, ICC, FCM

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 2B3

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: RUNX3

Immunogen: Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 44.4kDa

UniProt Accession: Q13761

Synonyms: AML2, CBFA3, PEBP2aC, FLJ34510, MGC16070

GeneID: 864

Research Use Only