Product Description

RYK Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34628-50, RA34628-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: receptor-like tyrosine kinase (RYK) Homo sapiens The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 66

Protein Molecular Weight (kDa): 66

Storage: -20°C/1 year

Human Gene ID: 6259

Human SwissProt Number: P34925

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only