S100B Monoclonal Antibody - BT-MCA3898

S100B Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3898-50, BT-MCA3898-100

Citations, Manuals and MSDS Available upon request.

Background: S100B (S100 calcium binding protein B) is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S100B are present in a variety of other tissues, and calbindin is present in intestine and kidney. Parvalbumin B is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Research Areas: Cell Biology, Signal Transduction, Epigenetics and Nuclear Signaling, Stem Cells

Target Protein: S100B

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 9A11B9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: S100B

Immunogen: Purified recombinant fragment of S100B expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: P04271

Synonyms: NEF, S100, S100beta

GeneID: 6285

Research Use Only