Product Description

S2P Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29623-50, RA29623-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: membrane bound transcription factor peptidase, site 2 (MBTPS2) Homo sapiens This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IP, IF/ICC, ELISA

Alternate Names: MBTPS2, S2P, Membrane-bound transcription factor site-2 protease, Endopeptidase S2P, Sterol regulatory element-binding proteins intramembrane protease, SREBPs intramembrane protease

Clonality: Polyclonal

Dilution: IP: 2-10µg/mL Western Blot: 1/500 - 1/2000.Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Storage: -20°C/1 year

Human Gene ID: 51360

Human SwissProt Number: O43462

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only