SAP30 Polyclonal Antibody - BT-AP14038

SAP30 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14038-20, BT-AP14038-50, BT-AP14038-100

Citations, Manuals and MSDS Available upon request.

Background: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.

Research Areas: Epigenetics and nuclear signaling

Target Protein: SAP30

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Histone deacetylase complex subunit SAP30

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O75446; Mouse: O88574

Synonyms: Histone deacetylase complex subunit SAP30;30 kDa Sin3-associated polypeptide;Sin3 corepressor complex subunit SAP30;Sin3-associated polypeptide p30

GeneID: Human: 8819

Research Use Only