SCN1A Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA34756-50, RA34756-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: sodium voltage-gated channel alpha subunit 1 (SCN1A) Homo sapiens Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits. This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, th Reactivity: Human, Rat Host: Rabbit Applications: WB, ELISA Clonality: Polyclonal Dilution: WB 1:500-2000 ELISA 1:5000-20000 Molecular Weight: 220 Protein Molecular Weight (kDa): 220 Storage: -20°C/1 year Human Gene ID: 6323 Human SwissProt Number: P35498 Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Research Use Only