Product Description

SDHB Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8003-50, BS8003-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sμlfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sμlfur centers of the enzyme. Sporadic and familial mutations in this gene resμlt in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF/ICC

Alternate Names: SDHB, CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human SDHB(NP_002991.2).

Dilution: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 32KDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P21912

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only