SEPT4 Polyclonal Antibody - BT-AP14124

SEPT4 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14124-20, BT-AP14124-50, BT-AP14124-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Research Areas: Cell biology; Signal transduction

Target Protein: SEPT4

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Septin-4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O43236; Mouse: P28661

Synonyms: Septin-4;Apoptosis-related protein in the TGF-beta signaling pathway;ARTS;Bradeion beta;Brain protein H5;CE5B3 beta;Cell division control-related protein 2;hCDCREL-2;Cerebral protein 7

GeneID: Human: 5414

Research Use Only