Product Description

Septin 5 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS72206-50, BS72206-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regμlatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regμlate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and resμlts in large mμltinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing resμlts in mμltiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also resμlts in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF/ICC

Alternate Names: SEPT5, CDCREL, CDCREL-1, CDCREL1, H5, HCDCREL-1, PNUTL1, septin-5

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human Septin 5(NP_002679.2).

Dilution: WB, 1:500 - 1:2000 IHC, 1:100 - 1:200 IF/ICC, 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 43KDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q99719

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only