SETD2 Monoclonal Antibody - BT-MCA4669

SETD2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4669-50, BT-MCA4669-100

Citations, Manuals and MSDS Available upon request.

Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]

Research Areas: Others

Target Protein: SETD2

Applications: FCM

Clonality: Monoclonal

Clone ID: 4G11E6

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: SETD2

Immunogen: Purified recombinant fragment of human SETD2 (AA: 2054-2245) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 287.6kDa

UniProt Accession: Q9BYW2

Synonyms: LLS, HYPB, SET2, HIF-1, HIP-1, KMT3A, HBP231, HSPC069, p231HBP

GeneID: 29072

Research Use Only