SFRP1 Polyclonal Antibody - BT-AP14149

SFRP1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14149-20, BT-AP14149-50, BT-AP14149-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

Research Areas: Cell biology; Developmental biology; Neuroscience; Stem cells

Target Protein: SFRP1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Secreted frizzled-related protein 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8N474; Mouse: Q8C4U3; Rat: Q9R168

Synonyms: Secreted frizzled-related protein 1;FRP-1;sFRP-1;Secreted apoptosis-related protein 2;SARP-2

GeneID: Human: 6422

Research Use Only