Product Description

Sgo2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29779-50, RA29779-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity). May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Belongs to the shugoshin family., subcellular location:In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase., subunit:Directly interacts with PPP2CA.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: IHC-p, IF (paraffin section), ELISA

Alternate Names: SGOL2, Shugoshin-like 2, Shugoshin-2, Sgo2, Tripin

Clonality: Polyclonal

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Storage: -20°C/1 year

Human Gene ID: 151246

Human SwissProt Number: Q562F6

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only