SH2B2 Monoclonal Antibody - BT-MCA4598

SH2B2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4598-50, BT-MCA4598-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

Research Areas: Others

Target Protein: SH2B2

Applications: IHC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 5E11G7

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: SH2B2

Immunogen: Purified recombinant fragment of human SH2B2 (AA: 497-676) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 67.7kDa

UniProt Accession: O14492

Synonyms: APS

GeneID: 10603

Research Use Only