SIGLEC5 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A4250-20, A4250-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig) -like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse
Protein Weight: 61kDa
Observed Molecular Weight: 70kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 8778
SWISS: O15389
Alternate Names: CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5; SIGLEC5
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Immunology Inflammation, CDs.
NCBI Alias: SIGLEC5
Research Use Only