Product Description

SIRT1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS80148-50, BS80148-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regμlate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellμlar regμlatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing resμlts in mμltiple transcript variants.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF/ICC, IP, ChIP

Alternate Names: SIR2, SIR2L1, SIR2alpha, SIRT1, sirtuin 1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human SIRT1(NP_036370.2).

Dilution: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 IP, 50 - 1:200 ChIP, 1:20 - 1:100

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Molecular Weight: 120kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96EB6

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only