SIVA1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6326-20, A6326-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 19kDa
Observed Molecular Weight: 15kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 10572
SWISS: O15304
Alternate Names: SIVA; CD27BP; Siva-1; Siva-2; SIVA1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, Cytokines.
NCBI Alias: SIVA1
Research Use Only