Product Description

SMAD2/SMAD3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS80508-50, BS80508-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modμlators that mediate mμltiple signaling pathways. This protein functions as a transcriptional modμlator activated by transforming growth factor-beta and is thought to play a role in the regμlation of carcinogenesis.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF/ICC

Alternate Names: HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SMAD2/SMAD3 (NP_005892.1).

Dilution: WB:1:500 - 1:1000
IHC:1:50 - 1:200
IF/ICC:1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SMAD2/SMAD3 polyclonal antibody detects endogenous levels of SMAD2/SMAD3 protein.

Molecular Weight: ~ 60 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P84022/Q15796

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only